Fig. 6

Effects of the resistance training intervention on cross-sectional area of muscle fiber types I and II in m. vastus lateralis in COPD (n = 18) and Healthy (n = 55). A presents comparison of overall training effects on fiber CSA between COPD and Healthy, measured as relative changes from baseline to after the training intervention (per study cluster; left panel) and as relative differences in change scores between study clusters (right panel). In these analyses, high- and low-load resistance training (10RM and 30RM, respectively) were combined, warranted by the lack of significant differences between training load conditions in (B, C), though COPD tended to show higher efficacy of 30RM resistance training for changes in fiber type I CSA. B, C presents comparisons of effects of 10RM and 30RM resistance training on fiber CSA in COPD (B) and Healthy (C) (i.e. per study cluster), measured as relative changes from baseline to after the training intervention (left panels) and as relative and numeric differences in change scores between load conditions (right panels). Data are presented as means with 95% confidence limits