Fig. 6
From: Circ_001209 aggravates diabetic retinal vascular dysfunction through regulating miR-15b-5p/COL12A1
Circ_001209 aggravates diabetes mellitus-induced retinal vascular dysfunction in vivo. The retinal tissue was taken from the AAV-ciR-NC or AAV-circ_001209 injected diabetic rat at 2 months after injection. The expression of circ_001209 (A), miR-15b-5p (B) and COL12A1 (C) in the retinal tissue was detected by qRT-PCR analysis. Hematoxylin and eosin (H&E) staining was used to detect the pathological tissue damage induced by diabetic retinopathy in rats. E TUNEL staining images for retinal and the quantization diagram. The data are presented as mean ± SD. n = 6 each group. Vs sham ± AAV-ciR-NC group, *P  <  0.05, **P <  0.01; vs STZ + AAV-ciR-NC group, #P  <  0.05