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Table 2 Incidence rates, hazard ratio, and confidence intervals of TB infection in different stratifications

From: Increased risk of pulmonary and extrapulmonary tuberculosis infection in patients with polycystic kidney disease: a nationwide population-based study with propensity score-matching analysis

Variables Non-PKD Cohort PKD Cohort PKD VS. Non-PKD
n = 6770 n = 6770 Crude HR Adjusted HR
Event Person years IR Event Person years IR (95% CI) (95% CI)
Overall 114 41,183 27.68 175 35,325 49.54 1.74(1.37–2.20)*** 1.91(1.51–2.43)***
 PTB 90 41,243 21.82 121 35,514 34.07 1.52(1.16–2.00)** 1.69(1.29–2.22)**
 EPTB 22 41,386 5.32 44 35,565 12.37 2.28(1.37–3.80)** 2.44(1.46–4.08)***
Gender
 Female 25 18,070 13.84 46 16,280 28.25 2.00(1.23–3.26)** 2.22(1.36–3.62)**
 Male 89 23,114 38.51 129 19,045 67.73 1.70(1.30–2.23)*** 1.84(1.4–2.41)***
Age at baseline
 20–49 5 14,842 3.37 14 14,217 9.85 2.88(1.04–7.99)* 3.29(1.14–9.47)*
 50–64 21 12,306 17.06 48 10,711 44.81 2.61(1.56–4.36)*** 2.68(1.6–4.49)***
  > 65 88 14,035 62.70 113 10,397 108.68 1.66(1.25–2.19)*** 1.66(1.25–2.19)***
Baseline comorbidity
 No 26 22,890 11.36 56 20,366 27.50 2.37(1.49–3.78)** 2.69(1.69–4.30)***
 Yes 88 18,294 48.10 119 14,960 79.55 1.60(1.22–2.11)*** 1.71(1.30–2.26)***
 Hypertension 57 11,064 51.52 88 9052 97.22 1.84(1.32–2.56)*** 1.89(1.35–2.64)***
 Hyperlipidemia 5 1918 26.07 14 1500 93.35 3.56(1.28–9.90)* 4.18(1.46–11.94)**
 Alcohol related disease 4 422 94.81 2 303 66.01 0.66(0.12–3.60) 1.52(0.18–13.01)
 Chronic kidney disease 45 6931 64.93 53 5666 93.54 1.40(0.94–2.08) 1.44(0.97–2.15)
 ESRD 14 3507 39.92 16 3030 52.80 1.28(0.62–2.62) 1.27(0.61–2.63)
 Chronic liver disease 20 2158 92.67 18 1654 108.85 1.13(0.60–2.14) 1.25(0.65–2.40)
 COPD 24 1583 151.66 22 1253 175.54 1.09(0.61–1.94) 1.19(0.66–2.15)
 Diabetes 15 2916 51.44 25 2437 102.57 1.95(1.03–3.69)* 1.92(1.01–3.66)*
 Bacterial infection 50 7999 62.51 47 6885 68.27 1.06(0.71–1.58) 1.12(0.75–1.68)
 Viral infection 15 2484 60.39 22 1880 117.03 1.86(0.96–3.59) 1.82(0.93–3.57)
 Pneumoconiosis 7 222 314.69 4 213 187.37 0.64(0.19–2.19) 0.69(0.17–2.72)
  1. IR incidence rates, per 10,000 person-years, HR hazard ratio, CI confidence interval
  2. Adjusted HR: adjusted for age, all comorbidities in Cox proportional hazards regression
  3. *p < 0.05, **p < 0.01, ***p < 0.001