Table 3 The results of univariate and multivariate Cox analysis of traditional prognostic factors and risk scores generated by the prediction model
From: The landscape of gene co-expression modules correlating with prognostic genetic abnormalities in AML
| Â | Univariate Cox analysis | Multivariate Cox analysis | ||||
|---|---|---|---|---|---|---|
Characteristics | Hazard Ratio | 95% CI | p value | Hazard Ratio | 95% CI | p value |
Age | 1.03 | 1.02–1.05 | 0 | 1.01 | 0.99–1.03 | 0.298 |
Blast_percentage | 1 | 0.99–1.02 | 0.443 | NA | NA | NA |
FAB | 1.06 | 0.94–1.2 | 0.351 | NA | NA | NA |
Induction | 3.51 | 2.19–5.61 | 0 | 1.84 | 0.98–3.46 | 0.057 |
Race | 0.86 | 0.66–1.13 | 0.287 | NA | NA | NA |
Risk_cytogenetic | 1.73 | 1.23–2.41 | 0.001 | 0.64 | 0.22–1.92 | 0.43 |
Risk_molecular | 1.83 | 1.31–2.56 | 0 | 3.36 | 1.2–9.44 | 0.021 |
Riskscore | 1.01 | 1–1.02 | 0.012 | 1.01 | 1–1.02 | 0.023 |
Sex | 1.05 | 0.69–1.57 | 0.831 | NA | NA | NA |
Transplantation | 0.41 | 0.27–0.62 | 0 | 0.42 | 0.25–0.72 | 0.002 |