Characterization of terminal-ileal and colonic Crohn’s disease in treatment-naïve paediatric patients based on transcriptomic profile using logistic regression

Table 1 Summary of number of CCD and ICD-specific genes with different expression types

Depending on the tissue type of α and β, CCD and ICD-specific genes were separately classified: when α = colon tissue type and β = ileum tissue type, the result would be CCD genes; when α = ileum tissue type and β = colon tissue type, the result would be ICD genes. To get significantly differentially expressed genes, genes with p-value of 0.05 and confidence interval 95% were set to be cutoff for CDα vs CDβ, NMα vs NMβ, and CDα vs NMα. To specifically expressed, gene were also selected from CD_β vs. NM_β, (p-value > 0.1). For each pattern graph, red, blue, and black line represents percentile of 75th, 25th, and median, respectively
CD: Crohn’s disease; NM: Normal (control) samples; CCD: colonic CD; NMC; normal colon; NMI: normal ileum; ICD: terminal-ileal CD; ≒: no differences (p-value > 0.1)

ISSN: 1479-5876