Skip to main content

Table 3 Fold over basal (FOB) in chronic ischemic and non-ischemic muscle

From: The effect of revascularization on recovery of mitochondrial respiration in peripheral artery disease: a case control study

Parameter FOB in chronic ischemic muscle (gastrocnemius muscle) FOB in non-ischemic muscle (lateral vastus muscle) p-value
CSA (nmol/min/mg protein) 1.37 (1.10–1.64) 0.93 (0.69–1.16) 0.020
MOctL per CSA 0.83 (0.44–1.22) 1.39 (0.74–2.05) 0.037
MOctP per CSA 0.87 (0.28–1.45) 1.47 (0.56–2.37) 0.020
P per CSA 0.64 (0.46–0.82) 1.16 (0.77–1.54) 0.011
E per CSA 0.61 (0.47–0.76) 1.02 (0.64–1.40) 0.010
  1. Fold over basal (FOB) in chronic ischemic and non-ischemic muscle; Data are expressed as median with IQR in brackets; A p-value < 0.05 is considered to be significant; CSA Citrate synthase activity, MOctL maximal respiration after titration of malate and octanoyl; MOctP maximal respiration after addition of ADP, P maximal respiration after addition of pyruvate and succinate; E maximal respiration after addition of FCCP