Table 3 Demographic profiles about the PD AAO GWAS dataset
Dataset | PD cases | Average age of onset of cases (range) | Sex ratio male/female of cases |
|---|---|---|---|
Dutch GWAS [23] | 764 | 54.94 (21–84) | 1.74 |
Finnish GWAS | 377 | 55.27 (30–66) | 1.19 |
German GWAS [24] | 663 | 55.84 (28–86) | 1.55 |
Harvard Biomarker Study (HBS) | 525 | 66.31 (35–89) | 1.92 |
McGill Parkinson’s | 580 | 65.56 (37–91) | 1.89 |
IPDGC NeuroX [25] | 5428 | 61.27 (20–89) | 1.82 |
NIA PD GWAS [24] | 845 | 58.25 (20–87) | 1.46 |
OsloParkinson’s Disease Study | 476 | 55.70 (24–83) | 1.8 |
Parkinson’s Disease Biomarker’s Program (PDBP) | 512 | 64.46 (34–87) | 1.59 |
Parkinson’s Progression Markers Initiative (PPMI) | 360 | 64.24 (36–87) | 2.03 |
PROBAND | 1815 | 66.25 (29–90) | 1.85 |
PROPARK | 235 | 55.69 (29–81) | 2.09 |
Baylor College of Medicine/University of Maryland | 764 | 64.83 (23–92) | 1.95 |
Spanish GWAS [26] | 1928 | 63.90 (20–95) | 1.35 |
Tuebingen Parkinson’s Disease cohort | 666 | 59.89 (23–87) | 1.78 |
WTCCC PD GWAS [27] | 1477 | 64.10 (23–96) | 1.6 |
System Genomics of Parkinson’s disease (SGPD) | 581 | 59.96 (24–84) | 1.75 |
Total IPDGC | 17,996 | 62.14 (20–96) | 1.7 |
23 and Me | 10,572 | 60.71 (40–97) | 1.54 |
Total | 28,568 | 61.71 (20–97) | 1.64 |