Table 3 Results of univariate and multivariate analysis for OS in non-M3 AML patients
Univariate | Multivariate | |||
|---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI) | P value | |
PRICKLE1 (high vs. low) | 2.324 (1.289–4.192) | 0.005 | 3.087 (1.288–7.397) | 0.012 |
Age (> median vs. < median) | 2.272 (1.270–4.067) | 0.006 | 2.028 (0.896–4.590) | 0.090 |
WBC (> median vs. < median) | 1.508 (0.828–2.746) | 0.179 | 1.743 (0.752–4.040) | 0.195 |
Cytogenetic risk (poor vs. intermediate vs. favorable) | 1.792 (1.095–2.935) | 0.020 | 1.259 (0.739–2.144) | 0.397 |
NPM1 (mutated vs. wild) | 0.990 (0.451–2.174) | 0.980 | 0.378 (0.099–1.445) | 0.155 |
FLT3-ITD (mutated vs. wild) | 1.379 (0.572–3.321) | 0.474 | 0.923 (0.226–3.770) | 0.912 |
CEBPA (mutated vs. wild) | 0.400 (0.141–1.132) | 0.084 | 0.407 (0.132–1.255) | 0.118 |
DNMT3A (mutated vs. wild) | 0.750 (0.180–3.128) | 0.693 | 0.688 (0.082–5.793) | 0.731 |
IDH1 (mutated vs. wild) | 1.449 (0.509–4.123) | 0.487 | 0.571 (0.159–2.047) | 0.389 |
IDH2 (mutated vs. wild) | 0.806 (0.246–2.641) | 0.721 | 0.527 (0.106–2.618) | 0.433 |