Fig. 5

Downregulation of UCA1 or upregulation of miR-122-5p promotes apoptosis and decreases proliferation of CD133⁺CaSki cells. a AnnexinV-FITC/PI double staining was used to detect the apoptosis of cells in each group. b Comparison of apoptosis rate in each group. c Comparison of proliferation difference in each group. N = 3, * P < 0.05 vs. the Exo + siRNA-NC group, # P < 0.05 vs. the Exo + mimic-NC group. & P < 0.05 vs. the Exo + pcDNA-UCA1 + mimic-NC group. Measurement data were depicted as mean ± standard deviation, comparisons among multiple groups were assessed by one-way analysis of variance followed with LSD-t