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Fig. 8 | Journal of Translational Medicine

Fig. 8

From: Deconvolution of sarcoma methylomes reveals varying degrees of immune cell infiltrates with association to genomic aberrations

Fig. 8

TILs are associated with a deletion of 13q14.2 in UPS. Samples were split into three equally sized groups based on their TIL score. The oncoprint shows deletions, fusions and SNVs enriched in the lower TIL score tertile for UPS. For each group and gene, the percentage of samples with at least one alteration is given. Additionally, the bottom heatmaps show matched gene expression data (pink: not available). With the exception of ATP7B, all of the deleted genes were located in the 13q14.2 region. The tumor suppressor gene RB1 was deleted in seven out of 15 samples belonging to the low TIL group

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