Fig. 2

STLMS core signature. The heatmap shows DNA methylation and mRNA expression for the top 100 genes in samples with a high proportion of LMC7. Samples are clustered within the same histological subtype in columns, and genes are clustered in rows. The three LMS subgroups shown in the annotations were assigned based on the proportions of LMC1 and 7. Group 1, associated with LMC7 mainly comprised STLMS, whereas group 2 (LMC1) was enriched for tumors belonging to ULMS. Leukocyte fraction scores are shown as estimated by [2]