Fig. 5

A combination of the percentages of IFN-γ⁺CD4⁺T cells and GrB⁺CD19⁺B cells as a novel marker can identify acute rejection. Correlations of the percentages of IFN-γ⁺CD4⁺T cells and the percentages of GrB⁺CD19⁺B cells (a); ROC curve analysis of percentages of IFN-γ⁺CD4⁺T cells and GrB⁺CD19⁺B cells and a combination of both as the new marker (b); The occurrence rate of acute rejection between liver transplant recipients with the novel marker > 62.93% and < 62.93% (c); Representative images of hematoxylin–eosin staining from liver transplant recipients with acute cellular rejection (d, e); Analysis of the percentages of IFN-γ⁺CD4⁺T cells and GrB⁺CD19⁺B cells and the novel marker between liver transplant recipients with mild and non-mild inflammation and damage (f, h). Bars represent mean and standard deviation. GrB granzyme B, ROC receiver operating characteristic, AUC area under the curve