Table 1 Characteristics of Study Participants and Pulmonary Nodules at Baseline
Characteristics | Lung cancer (n = 61) | Cancer-free (n = 31) | p-value |
|---|---|---|---|
Age (year), mean ± SD | 58.1 ± 10.1 | 55.7 ± 10.8 | 0.276 |
Sex, n (%) | |||
 Man | 15 (24.6) | 12 (38.7) | 0.226 |
 Woman | 46 (75.4) | 19 (61.3) |  |
Smoking status, n (%)a | |||
 Currently smoke | 3 (4.9) | 2 (6.5) | 0.847 |
 Quit smoke | 2 (3.3) | 0 (0.0) |  |
 Never smoke | 56 (91.8) | 29 (93.6) |  |
Cancer history, n (%) | |||
 Personal | 8 (13.1) | 1 (3.2) | 0.264 |
 Family | 1 (1.6) | 0 (0.0) |  > .999 |
No. of screening, n (%) | |||
 1 | 33 (54.1) | 25 (80.7) | 0.033 |
 2 | 22 (36.1) | 4 (12.9) |  |
 ≥ 3 | 6 (9.8) | 2 (6.5) |  |
Nodule location, n (%) | |||
 Left upper lobe | 19 (31.2) | 8 (25.8) | 0.024 |
 Left lower lobe | 6 (9.8) | 10 (32.3) |  |
 Right upper lobe | 29 (47.5) | 7 (22.6) |  |
 Right middle lobe | 1 (1.6) | 1 (3.2) |  |
 Right lower lobe | 6 (9.8) | 5 (16.1) |  |
Diameter (mm) | |||
 < 6 | 2 (3.3) | 0 (0.0) | 0.807 |
 6 ~  | 3 (4.9) | 1 (3.2) |  |
 8 ~  | 8 (13.1) | 7 (22.6) |  |
 10 ~  | 27 (44.3) | 12 (38.7) |  |
 15 ~  | 12 (19.7) | 5 (16.1) |  |
 20 ~  | 9 (14.8) | 6 (19.4) |  |
Nodule type | |||
 Solid | 4 (6.6) | 11 (35.5) |  < 0.001 |
 Part-solid | 42 (68.9) | 18 (58.1) |  |
 Non-solid | 15 (24.6) | 2 (6.5) |  |
Other semantic phenotype | |||
 Lobular | 35 (57.4) | 20 (64.5) | 0.653 |
 Spiculated | 20 (32.8) | 7 (22.6) | 0.344 |
 Juxtapleural | 9 (14.8) | 10 (32.3) | 0.061 |
 Pleural tag | 10 (16.4) | 2 (6.5) | 0.326 |