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Table 1 Characteristics of Study Participants and Pulmonary Nodules at Baseline

From: Optimizing the timing of diagnostic testing after positive findings in lung cancer screening: a proof of concept radiomics study

Characteristics Lung cancer (n = 61) Cancer-free (n = 31) p-value
Age (year), mean ± SD 58.1 ± 10.1 55.7 ± 10.8 0.276
Sex, n (%)
 Man 15 (24.6) 12 (38.7) 0.226
 Woman 46 (75.4) 19 (61.3)  
Smoking status, n (%)a
 Currently smoke 3 (4.9) 2 (6.5) 0.847
 Quit smoke 2 (3.3) 0 (0.0)  
 Never smoke 56 (91.8) 29 (93.6)  
Cancer history, n (%)
 Personal 8 (13.1) 1 (3.2) 0.264
 Family 1 (1.6) 0 (0.0)  > .999
No. of screening, n (%)
 1 33 (54.1) 25 (80.7) 0.033
 2 22 (36.1) 4 (12.9)  
 ≥ 3 6 (9.8) 2 (6.5)  
Nodule location, n (%)
 Left upper lobe 19 (31.2) 8 (25.8) 0.024
 Left lower lobe 6 (9.8) 10 (32.3)  
 Right upper lobe 29 (47.5) 7 (22.6)  
 Right middle lobe 1 (1.6) 1 (3.2)  
 Right lower lobe 6 (9.8) 5 (16.1)  
Diameter (mm)
 < 6 2 (3.3) 0 (0.0) 0.807
 6 ~  3 (4.9) 1 (3.2)  
 8 ~  8 (13.1) 7 (22.6)  
 10 ~  27 (44.3) 12 (38.7)  
 15 ~  12 (19.7) 5 (16.1)  
 20 ~  9 (14.8) 6 (19.4)  
Nodule type
 Solid 4 (6.6) 11 (35.5)  < 0.001
 Part-solid 42 (68.9) 18 (58.1)  
 Non-solid 15 (24.6) 2 (6.5)  
Other semantic phenotype
 Lobular 35 (57.4) 20 (64.5) 0.653
 Spiculated 20 (32.8) 7 (22.6) 0.344
 Juxtapleural 9 (14.8) 10 (32.3) 0.061
 Pleural tag 10 (16.4) 2 (6.5) 0.326
  1. In cases in which more than one pulmonary nodule was present, data on nodule characteristics are shown for the one that had the greatest area in the transaxial plane
  2. aCurrent smoker defined as ≥ 10 pack-years; quit smoking defined as ≥ 5 years’ cessation