Fig. 2

Cisplatin influenced the composition of faecal microbiota in mice. a–d Alpha diversity indices (Chao 1, observed OTUs, PD whole tree, and Shannon) in bacterial microbiomes. e Principal coordinate analysis (PCoA) based on the Binary Jaccard distance analysis of operational taxonomic units (OTUs). f, g Relative abundance at the phylum and genus level between control and cisplatin-treated groups. h LDA along with effect size measurements was applied to present the enriched bacteria in each group in faecal content. i–k Relative abundance of Escherichia, Parabacteroides and Ruminococcus between control and cisplatin-treated groups. l Predicted pathways enriched in cisplatin group as assessed by PICRUSt. n = 9 per group. *P < 0.05