Fig. 3

a The network exhibits the correlation between the drug sensitivity in cancer cell lines from GDSC and the expression level of 685 invasiveness-associated DEGs across cancer types. Dark blue dots represent genes, while dots with other colors represent the anti-cancer drugs targeting different biological pathways. Red lines indicate positive correlation and blue lines indicate negative. b–d Genes significantly correlated with three important anti-cancer drugs—NU7441 (b), SB216763 (c), and KU-55933 (d)—were highlighted