Fig. 6From: M2 macrophage-derived exosomal microRNAs inhibit cell migration and invasion in gliomas through PI3K/AKT/mTOR signaling pathwayKnockdown of CCND1 or RAP1B inhibited the PI3K/AKT/mTOR signaling pathway. Western blot assays showed that the phosphorylation levels of AKT and mTOR were reduced compared with the control groups after interfering the expression of CCND1 or RAP1B in a T98 and b U251 cell lines. **P < 0.01; *P < 0.05Back to article page