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Table 9 Crossover analysis of SNP rs1044250 and WM on ΔSBP, ΔDBP and ΔHDL-c

From: Cross-talk between ANGPTL4 gene SNP Rs1044250 and weight management is a risk factor of metabolic syndrome

  β OR p S
ΔSBP
 WM 0.024 1.024 0.477 0.558
 Dom 0.193 1.212 < 0.001
 Dom*WM − 0.093 0.911 0.013
ΔDBP
 WM 0.027 1.027 0.429 0.696
 Dom 0.241 1.273 < 0.001
 Dom*WM − 0.078 0.925 0.035
ΔHDL-c
 WM − 0.066 0.936 0.053 0.106a
 Dom 0.017 1.017 0.620
 Dom*WM 0.054 1.056 0.154
  1. SBP: systolic blood pressure; DBP: diastolic blood pressure; TG: triglyceride; HDL-c: high-density lipoprotein-cholesterol; WM: Weight loss = 0, Weight gain = 1; Dom, CC = 0, CT + TT = 1, OR: odds ratio; S: synergy index; S = [EXP(βWM + βDom + βDom*WM) − 1]/[EXP(βWM) + EXP(βDom)—2]
  2. aThe denominator is calibrated from negative to positive