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Table 9 Crossover analysis of SNP rs1044250 and WM on ΔSBP, ΔDBP and ΔHDL-c

From: Cross-talk between ANGPTL4 gene SNP Rs1044250 and weight management is a risk factor of metabolic syndrome

 

β

OR

p

S

ΔSBP

 WM

0.024

1.024

0.477

0.558

 Dom

0.193

1.212

< 0.001

 Dom*WM

− 0.093

0.911

0.013

ΔDBP

 WM

0.027

1.027

0.429

0.696

 Dom

0.241

1.273

< 0.001

 Dom*WM

− 0.078

0.925

0.035

ΔHDL-c

 WM

− 0.066

0.936

0.053

0.106a

 Dom

0.017

1.017

0.620

 Dom*WM

0.054

1.056

0.154

  1. SBP: systolic blood pressure; DBP: diastolic blood pressure; TG: triglyceride; HDL-c: high-density lipoprotein-cholesterol; WM: Weight loss = 0, Weight gain = 1; Dom, CC = 0, CT + TT = 1, OR: odds ratio; S: synergy index; S = [EXP(βWM + βDom + βDom*WM) − 1]/[EXP(βWM) + EXP(βDom)—2]
  2. aThe denominator is calibrated from negative to positive
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Journal of Translational Medicine

ISSN: 1479-5876

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