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Table 3 Distribution of SNP rs1044250 genotypes and alleles in Mets and Mets components

From: Cross-talk between ANGPTL4 gene SNP Rs1044250 and weight management is a risk factor of metabolic syndrome

 

n

Genotypes

χ2

p

Alleles

χ2

p

CC

CT

TT

C

T

Mets

 Control group

1029

900 (87.5%)

125 (12.1%)

4 (0.4%)

25.556

 < 0.001

1925 (93.5%)

133 (6.5%)

25.991

 < 0.001

 Mets group

1018

811 (79.7%)

191 (18.8%)

16 (1.6%)

1847 (90.7%)

189 (9.3%)

Component

 Normal BP

961

760 (86.9%)

111 (12.7%)

4 (0.5%)

13.68

0.001

1631 (93.2%)

119 (6.8%)

13.834

 < 0.001

 Elevated BP

1169

951 (81.1%)

205 (17.5%)

20 (1.0%)

2107 (89.1%)

237 (10.1%)

 Normal TG

1347

1164 (85.0%)

196 (14.3%)

10 (0.7%)

6.96

0.031

2524 (92.1%)

216 (7.9%)

6.888

0.009

 Increased TG

688

547 (80.8%)

120 (17.7%)

10 (0.7%)

1214 (89.7%)

140 (10.3%)

 Normal WC

1318

1009 (86.8%)

149 (12.8%)

4 (0.3%)

26.308

 < 0.001

2441 (92.6%)

195 (7.4%)

9.741

0.002

 Increased WC

717

702 (79.3%)

167 (18.9%)

16 (1.8%)

1299 (90.6%)

135 (9.4%)

 Normal FPG

1721

1324 (84.8%)

222 (14.2%)

15 (1.0%)

7.504

0.023

2870 (91.9%)

252 (8.1%)

6.447

0.011

 Increased FPG

314

387 (79.6%)

94 (19.3%)

5 (1.0%)

868 (89.3%)

104 (10.7%)

 Normal HDL

1811

1216 (83.5%)

225 (15.5%)

15 (1.0%)

0.15

0.928

2657 (91.2%)

255 (8.8%)

0.048

0.827

 Decreased HDL

224

495 (83.8%)

91 (15.4%)

5 (0.8.%)

1081 (91.5%)

101 (8.5%)

  1. Mets, metabolic syndrome; BP, blood pressure; TG, triglyceride; HDL-c, high-density lipoprotein-cholesterol; WC, waist circumference; FPG, fasting plasma glucose