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Table 1 Comparison of calculation speed between proposed method and five state-of-the-art prediction methods

From: MDAKRLS: Predicting human microbe-disease association based on Kronecker regularized least squares and similarities

Method 5-fold CV Global LOOCV
Average running time (s) Running time (s)
Proposed method 1.5604 \(\pm\) 0.1290 7.4807
KATZHMDA 1.7240 \(\pm\) 0.1190 8.6369
LRLSHMDA 1.8275 \(\pm\) 0.2236 29.1313
BiRWHMDA 1.6293 \(\pm\) 0.1057 11.7000
GRNMFHMDA 1.9593 \(\pm\) 0.1669 30.1469
NTSHMDA 1.8302 + -0.8365 19.4239