Fig. 7

Long-term L. edodes derived β-glucan supplementation alleviated the synaptic impairment in the prefrontal cortex of mice fed HF diet. a Representative electron micrograph of synaptic ultrastructure in the prefrontal cortex (PFC) region, b statistical analysis of PSD thickness, c statistical analysis of the width of synaptic cleft, d statistical analysis of the curvature of synaptic interface in the PFC, e protein expression levels of BDNF and PSD-95 in PFC. Data are presented as mean ± SEM. n = 3 per group. ^*P < 0.05, vs lab chow diet group (LC); ^#P < 0.05, vs high-fat diet group (HF). HFL, L. edodes β-glucan supplementation in HF diet group