Fig. 1

Short-term L. edodes derived β-glucan supplementation attenuated the gut microbiota dysbiosis induced by HF diet. a The relative abundance of Firmicutes, b the relative abundance of Bacteroidetes, c the ratio of Firmicutes (FM) to Bacteroidetes (BO), d the relative abundance of Proteobacteria, e the relative abundance of Actinobacteria, f the Shannon index, g the linear discriminant analysis (LDA) effect size results on mice gut microbiomes, h the plasma LPS levels in the sera, i body weight, j energy intake. Data are presented as mean ± standard error of means (SEM). n = 6 per group. ^*P < 0.05, ^***P < 0.001, vs lab chow diet group (LC); ^#P < 0.05, ^## P < 0.01, ^###P < 0.001, vs high-fat diet group (HF). HFL, L. edodes β-glucan supplementation in HF diet group