The potential role of chemotaxis and the complement system in the formation and progression of thoracic aortic aneurysms inferred from the weighted gene coexpression network analysis

Table 1 The top 30 most differentially expressed genes between normal and dilated thoracic aortic aneurysms (TAAs)

Gene symbol	Log₂(FC)^a	FDR	Gene symbol	Log₂(FC)^a	FDR^¶
CX3CR1	1.818	< 0.001^***	SEMA3D	− 1.628	0.001^**
HLA-DPA1	1.529	< 0.001^***	PCDH20	− 1.408	< 0.001^***
C3	1.390	0.013^**	CDH8	− 1.310	< 0.001^***
CD74	1.335	0.003^**	CNTN1	− 1.246	0.009^**
HLA-DRA	1.280	0.003^**	DND1	− 1.199	0.004^**
CD53	1.224	0.007^**	PROM1	− 1.155	0.015^*
FCGR3A	1.175	0.005^**	CNTN4	− 1.115	0.007^**
MFAP5	1.146	0.018^*	RYR2	− 1.062	0.008^**
C3AR1	1.141	0.004^**	SEMA3E	− 0.997	0.001^**
MS4A4A	1.122	0.014^*
LAPTM5	1.118	0.017^*
EVI2B	1.118	0.009^**
HLA-DPB1	1.095	0.009^**
CYBB	1.075	0.010^*
SFRP4	1.074	0.001^**
LCP1	1.022	0.017^*
C1QC	1.017	0.007^**
ALOX5AP	1.011	0.013^*
PTPRC	1.001	0.016^*
TLR7	0.998	0.001^**
CXCR4	0.997	0.023^*

ISSN: 1479-5876