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Table 1 The top 30 most differentially expressed genes between normal and dilated thoracic aortic aneurysms (TAAs)

From: The potential role of chemotaxis and the complement system in the formation and progression of thoracic aortic aneurysms inferred from the weighted gene coexpression network analysis

Gene symbol Log2(FC)a FDR Gene symbol Log2(FC)a FDR
CX3CR1 1.818  < 0.001*** SEMA3D − 1.628 0.001**
HLA-DPA1 1.529  < 0.001*** PCDH20 − 1.408  < 0.001***
C3 1.390 0.013** CDH8 − 1.310  < 0.001***
CD74 1.335 0.003** CNTN1 − 1.246 0.009**
HLA-DRA 1.280 0.003** DND1 − 1.199 0.004**
CD53 1.224 0.007** PROM1 − 1.155 0.015*
FCGR3A 1.175 0.005** CNTN4 − 1.115 0.007**
MFAP5 1.146 0.018* RYR2 − 1.062 0.008**
C3AR1 1.141 0.004** SEMA3E − 0.997 0.001**
MS4A4A 1.122 0.014*    
LAPTM5 1.118 0.017*    
EVI2B 1.118 0.009**    
HLA-DPB1 1.095 0.009**    
CYBB 1.075 0.010*    
SFRP4 1.074 0.001**    
LCP1 1.022 0.017*    
C1QC 1.017 0.007**    
ALOX5AP 1.011 0.013*    
PTPRC 1.001 0.016*    
TLR7 0.998 0.001**    
CXCR4 0.997 0.023*    
  1. Log2FC: Log2 fold change; FDR: false discovery rate
  2. FDR was calculated by p value from Wilcoxon test
  3. *marked significant differences. *FDR < 0.05, **FDR < 0.01, ***FDR < 0.001
  4. aLog2FC = Log2(mean expression of TAA group/ mean expression of control group)