Fig. 6

Representative images of hematoxylin/eosin (a, c) and Masson trichrome staining (b, d) of sensor implantation sites collected on the day of insertion (a, b) and 5 days after (c, d). a Normal muscular parenchyma delimitating the area of implantation without any inflammatory reaction at 5 ×; b Normal muscular parenchyma delimitating the area of implantation without any deposit of collagen fibers at × 20; c Muscular parenchyma delimitating the area of implantation with sub-acute inflammatory reaction at × 5; d Muscular parenchyma delimitating the area of implantation with deposit of collagen fibers at × 20. Inflammatory cell identification: Neutrophils: granulate cytoplasm; Monocytes: nucleus kidney shaped with foamy cytoplasm; Lymphocytes: dark nucleus with a small basophilic cytoplasm; giant multinucleated cells: large cells with multiple nucleus. Deposit of collagen observed as fibers stained with aniline blue