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Table 4 Correlation between the expression of KPNA2 and CBX8 in tissues and the characteristics of clinical cases

From: KPNA2 interaction with CBX8 contributes to the development and progression of bladder cancer by mediating the PRDM1/c-FOS pathway

Group

Cases

KPNA2 expression

p

CBX8 expression

p

Downregulate

Upregulate

Downregulate

Upregulate

Age

 > 60

15

5

10

> 0.05

7

8

> 0.05

 ≤ 60

30

17

13

16

14

Gender

 Male

35

19

16

> 0.05

18

17

> 0.05

 Female

10

3

7

5

5

TNM staging

 G1

17

5

12

< 0.05

5

12

< 0.05

 G2–G3

28

17

11

18

10

Clinical staging

 T1

24

4

20

< 0.05

8

16

< 0.05

 T2–T3

21

18

3

15

6

Smoking history

 Yes

28

15

13

> 0.05

13

15

> 0.05

 No

17

7

10

10

7

Gross hematuria

 Yes

30

15

15

> 0.05

16

14

> 0.05

 No

15

7

8

 

7

8

 

Metastasis

 Yes

14

11

3

< 0.05

11

3

< 0.05

 No

31

11

20

12

19

Recurrence

 Yes

19

15

4

< 0.05

14

5

< 0.05

 No

26

7

19

9

17