Fig. 4

Detailed information relating to changes in the biological function of DEGs in datasets through the enrichment analyses. a Heatmap of enriched terms across input gene expressed matrix of six datasets, via the Metascape. b Network of enriched terms colored by cluster identity, where nodes that share the same cluster identity are typically close to each other. c Network of enriched terms and genes colored by datases, where terms containing more genes tend to have a more significant. d The gene–gene interaction network for DEGs was analyzed using the GeneMANIA database. The 20 most frequently changed neighboring genes are shown. Each node represents a gene. The node color represents the possible functions of the respective gene