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Table 3 15 hub genes identified by five algorithms of cytoHubba

From: Three hematologic/immune system-specific expressed genes are considered as the potential biomarkers for the diagnosis of early rheumatoid arthritis through bioinformatics analysis

Gene symbol Description log2FC Q value Regulation
CXCL13 C–X–C motif chemokine ligand 13 2.846 0.012 Up
CD52 CD52 molecule 1.928 0.004 Up
GZMA Qranzyme A 1.753 0.022 Up
CD27 CD27 molecule 1.419 0.004 Up
CEP55 Centrosomal protein 55 1.264 0.01 Up
SKA3 Spindle and kinetochore associated complex subunit 3 1.215 3.03E−07 Up
IL21R Interleukin 21 receptor 1.208 7E−04 Up
DLGAP5 DLG associated protein 5 1.172 0.027 Up
PRC1 Protein regulator of cytokinesis 1 1.112 0.042 Up
EOMES eomesodermi 1.108 0.031 Up
TTK TTK protein kinas 1.065 0.006 Up
CDCA8 Cell division cycle associated 8 1.049 1.74E−08 Up
UHRF1 Ubiquitin-like with PHD and ring finger domains 1 1.048 0.016 Up
KIAA0101 PCNA clamp associated factor 1.017 0.013 Up
FNBP1L Formin binding protein 1 like −1.325 0.004 Down
  1. Annotation: FC: fold change, Q value: adjust P-value. The gene symbol in bold indicates eight hematologic/immune system-specific expressed hub genes