Skip to main content

Table 5 Included RCTs with diagnostic inclusion criteria with PEM as a required criterion (ME patients)

From: The evidence base for physiotherapy in myalgic encephalomyelitis/chronic fatigue syndrome when considering post-exertional malaise: a systematic review and narrative synthesis

Author,
Year
Country
Intervention (I) Comparison (C) Participants details (I/C)
Number allocated (N),
Mean age (year)
Gender (% female)
Diagnostic criteria Duration
Session duration
Frequency
No. of sessions (ss),
period (# weeks)
Outcome measure momentsa (weeks) Main outcome measures
1 Primary
2 Secondary
Adverse events
Treatment withdrawn
(I/C)
ITTb
Results (benefits), compared to controlc
Concl.—authors own conclusion
Pinxsterhuis et al
2017 [67]
Norway
Group-based self-management education, based on a self-efficacy theory and the ‘energy envelope’ theory (pacing) CAU N = 146 (73/73)
Age: 44
94% / 82%
CCC and CDC-94/Fukuda criteria 2.5 h
every 2 weeks,
16 weeks
26
52
1: SF-36
2: FSS, SES, ICQ
No
2/6
No
Short: SF-36 ns, FSS (C) p < 0.05, SES p < 0.05, ICQ ns
Long: all outcome ns
Concl.: this self-management program for CFS patients did not show a sustained effect
  1. Ss: sessions: ns non-significant, CAU: Care As Usual, FSS: Fatigue Severity Scale; ICQ: Illness-Cognition Questionnaire; SES: Self-Efficacy Scale; SF-36: Short Form Health Survey
  2. aRand: from randomisation moment, basel.: from baseline, post: (at) post-treatement
  3. bData for at least one key outcome was analyzed by ‘intention to treat’ analysis (ITT)
  4. cResults in favour of intervention. If results favours comparison intervention, ‘[C]’ is added. Post: post-treatment, Short-time follow-up, Long-longtime follow-up
  5. d‘Second-version’, with unknown modifications