Fig. 2

a Heatmap of Receptor Binding Domain variants geographical distribution by normalized frequency. Countries with low occurrences of RBD variants (less than 5) were removed. b Multiple Correspondence Analysis (MCA) of Country-RBD variant association. c Evolution of S447N and N439K in space and time. Y-axis represents the relative frequency of that mutation in every country isolate set for each month. X-axis: months in 2020, as annotated in GISAID sequences. Every bar is annotated with absolute counts