Fig. 6

Translational study in human sera coming from patients affected by FH (n = 20) and healthy subjects (n = 20) (discovery cohort). Quantification of selected marker candidates (CRP, PCSK9, ApoC-III, sICAM-1, AGT, PON-1, FETUB, VKDP-S, and BGN) in crude serum samples by colorimetric ELISA. Protein levels are presented as mean ± SEM. *, **, and *** indicate P < 0.05, P < 0.01, P < 0.001, respectively. FH + S – FH patients receiving statin therapy