Fig. 2
IL-33 enhanced HCC tumourigenesis. C57BL/6 mice were injected subcutaneously with Hepa1-6 cells (8 × 106) and treated with or without IL-33 protein (0.4 µg/mouse) in PBS intraperitoneally every other day. a Gross view of mice and b tumours after euthanasia of mice. c An histogram of tumour weight was presented from both groups of mice. d Tumour volume changed over time in two groups. e H&E staining images of tumour tissues from both groups of mice were presented. f Ki67 protein expression was detected by IHC. g The effect of IL-33 on Hepa1-6 cell proliferation was observed by CCK8 in vitro. PBS phosphate-buffered saline, H&E haematoxylin and eosin, IHC immunohistochemistry, CCK8 cell counting kit 8