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Table 6 Predictive performance of NLR, D-dimer, combined index and SOFA for severe COVID-19 in middle-aged (40–59 years) patients without comorbidities

From: Risk factors for severe COVID-19 in middle-aged patients without comorbidities: a multicentre retrospective study

Variables

AUC

Cut-off

95%CI

Sensitivity

Specificity

p valuea

NLR

0.862

5.03

0.751–0.973

88.2%

66.2%

 < 0.001

D-dimer > 1 μg/ml

0.800

–

0.684–0.915

82.4%

77.6%

 < 0.001

Combined index

0.916

–

0.855–0.977

82.4%

82.7%

 < 0.001

SOFA

0.750

2.0

0.602–0.987

70.6%

70.4%

0.001

  1. COVID-19 coronavirus disease 2019, AUC area under the curve, CI confidence interval, NLR neutrophil to lymphocyte ratio, Combined index combined NLR and D-dimer > 1 μg/ml, SOFA Sequential Organ Failure Assessment
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Journal of Translational Medicine

ISSN: 1479-5876

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