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Table 2 The top 20 up-/down-regulated DE-exo-miRs between different genotypes of KATP rs1799858 in subjects with elevated LDL-C (≥ 1.8 mmol/L) serum level

From: Plasma exosome-derived microRNAs expression profiling and bioinformatics analysis under cross-talk between increased low-density lipoprotein cholesterol level and ATP-sensitive potassium channels variant rs1799858

  miR ID Genotypes Fold P value Up/down
CC TT + CT
1 hsa-miR-483-5p 138.64 1028.68 2.89 1.78E−06 Up
2 hsa-miR-22-3p 9312.58 23,298.12 1.32 4.70E−06 Up
3 hsa-miR-490-3p 3.77 16.62 2.14 6.70E−06 Up
4 hsa-miR-378 g 17.15 52.60 1.62 8.25E−06 Up
5 hsa-miR-320e 170.32 439.14 1.37 1.98E−05 Up
6 hsa-miR-6515-5p 77.16 281.87 1.87 3.10E−05 Up
7 hsa-miR-31-5p 0.61 13.52 4.46 5.05E−05 Up
8 hsa-miR-320b 12,738.79 29,415.44 1.21 0.000119 Up
9 hsa-miR-210-3p 56.64 116.91 1.05 0.000129 Up
10 hsa-miR-17-3p 4.39 15.38 1.81 0.000223 Up
11 hsa-miR-320d 1301.14 3686.95 1.50 0.000526 Up
12 hsa-miR-6807-5p 3.46 7.45 1.11 0.000662 Up
13 hsa-miR-378b 2.62 7.60 1.54 0.000900 Up
14 hsa-miR-378a-3p 6006.05 12,280.17 1.03 0.001102 Up
15 hsa-miR-497-5p 0.59 2.72 2.22 0.001576 Up
16 hsa-miR-499a-5p 26.22 179.18 2.77 0.000640 Up
17 hsa-miR-208b-3p 2.28 20.72 3.18 0.002234 Up
18 hsa-miR-33a-5p 1.44 3.95 1.46 0.006131 Up
19 hsa-miR-3611 0.63 2.01 1.68 0.009428 Up
20 hsa-miR-126-5p 147.59 328.41 1.15 0.009467 Up
21 hsa-miR-6780a-5p 3.57 0.83 − 2.11 0.001143 Down
22 hsa-miR-619-5p 10.44 3.59 − 1.54 0.002449 Down
23 hsa-let-7e-5p 273.17 100.47 − 1.44 0.003298 Down
24 hsa-let-7i-5p 38,517.70 18,945.74 − 1.02 0.014038 Down
25 hsa-let-7g-5p 8191.48 3359.58 − 1.29 0.028204 Down
26 hsa-let-7a-5p 21,006.44 10,351.20 − 1.02 0.030679 Down
27 hsa-let-7f-5p 15,772.96 7041.42 − 1.16 0.041781 Down
28 hsa-miR-641 45.00 16.81 − 1.42 0.008062 Down
29 hsa-miR-200a-5p 3.47 1.54 − 1.17 0.013147 Down
30 hsa-miR-581 6.52 2.88 − 1.18 0.017211 Down
31 hsa-miR-222-3p 2679.15 1329.02 − 1.01 0.022200 Down
32 hsa-miR-605-3p 6.00 2.44 − 1.30 0.023085 Down
33 hsa-miR-548ar-3p 4.47 1.36 − 1.72 0.023611 Down
34 hsa-miR-221-5p 55.87 26.49 − 1.08 0.024990 Down
35 hsa-miR-135a-3p 1.34 0.38 − 1.80 0.026614 Down
36 hsa-miR-451b 3.15 1.08 − 1.54 0.027450 Down
37 hsa-miR-6721-5p 4.49 1.92 − 1.23 0.014197 Down
38 hsa-miR-98-5p 291.28 123.52 − 1.24 0.029034 Down
39 hsa-miR-4664-3p 19.91 9.87 − 1.01 0.038673 Down
40 hsa-miR-224-5p 145.46 61.90 − 1.23 0.042962 Down