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Table 2 The top 20 up-/down-regulated DE-exo-miRs between different genotypes of KATP rs1799858 in subjects with elevated LDL-C (≥ 1.8 mmol/L) serum level

From: Plasma exosome-derived microRNAs expression profiling and bioinformatics analysis under cross-talk between increased low-density lipoprotein cholesterol level and ATP-sensitive potassium channels variant rs1799858

 

miR ID

Genotypes

Fold

P value

Up/down

CC

TT + CT

1

hsa-miR-483-5p

138.64

1028.68

2.89

1.78E−06

Up

2

hsa-miR-22-3p

9312.58

23,298.12

1.32

4.70E−06

Up

3

hsa-miR-490-3p

3.77

16.62

2.14

6.70E−06

Up

4

hsa-miR-378 g

17.15

52.60

1.62

8.25E−06

Up

5

hsa-miR-320e

170.32

439.14

1.37

1.98E−05

Up

6

hsa-miR-6515-5p

77.16

281.87

1.87

3.10E−05

Up

7

hsa-miR-31-5p

0.61

13.52

4.46

5.05E−05

Up

8

hsa-miR-320b

12,738.79

29,415.44

1.21

0.000119

Up

9

hsa-miR-210-3p

56.64

116.91

1.05

0.000129

Up

10

hsa-miR-17-3p

4.39

15.38

1.81

0.000223

Up

11

hsa-miR-320d

1301.14

3686.95

1.50

0.000526

Up

12

hsa-miR-6807-5p

3.46

7.45

1.11

0.000662

Up

13

hsa-miR-378b

2.62

7.60

1.54

0.000900

Up

14

hsa-miR-378a-3p

6006.05

12,280.17

1.03

0.001102

Up

15

hsa-miR-497-5p

0.59

2.72

2.22

0.001576

Up

16

hsa-miR-499a-5p

26.22

179.18

2.77

0.000640

Up

17

hsa-miR-208b-3p

2.28

20.72

3.18

0.002234

Up

18

hsa-miR-33a-5p

1.44

3.95

1.46

0.006131

Up

19

hsa-miR-3611

0.63

2.01

1.68

0.009428

Up

20

hsa-miR-126-5p

147.59

328.41

1.15

0.009467

Up

21

hsa-miR-6780a-5p

3.57

0.83

− 2.11

0.001143

Down

22

hsa-miR-619-5p

10.44

3.59

− 1.54

0.002449

Down

23

hsa-let-7e-5p

273.17

100.47

− 1.44

0.003298

Down

24

hsa-let-7i-5p

38,517.70

18,945.74

− 1.02

0.014038

Down

25

hsa-let-7g-5p

8191.48

3359.58

− 1.29

0.028204

Down

26

hsa-let-7a-5p

21,006.44

10,351.20

− 1.02

0.030679

Down

27

hsa-let-7f-5p

15,772.96

7041.42

− 1.16

0.041781

Down

28

hsa-miR-641

45.00

16.81

− 1.42

0.008062

Down

29

hsa-miR-200a-5p

3.47

1.54

− 1.17

0.013147

Down

30

hsa-miR-581

6.52

2.88

− 1.18

0.017211

Down

31

hsa-miR-222-3p

2679.15

1329.02

− 1.01

0.022200

Down

32

hsa-miR-605-3p

6.00

2.44

− 1.30

0.023085

Down

33

hsa-miR-548ar-3p

4.47

1.36

− 1.72

0.023611

Down

34

hsa-miR-221-5p

55.87

26.49

− 1.08

0.024990

Down

35

hsa-miR-135a-3p

1.34

0.38

− 1.80

0.026614

Down

36

hsa-miR-451b

3.15

1.08

− 1.54

0.027450

Down

37

hsa-miR-6721-5p

4.49

1.92

− 1.23

0.014197

Down

38

hsa-miR-98-5p

291.28

123.52

− 1.24

0.029034

Down

39

hsa-miR-4664-3p

19.91

9.87

− 1.01

0.038673

Down

40

hsa-miR-224-5p

145.46

61.90

− 1.23

0.042962

Down

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Journal of Translational Medicine

ISSN: 1479-5876

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