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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Immune landscape and prognostic immune-related genes in KRAS-mutant colorectal cancer patients

Fig. 4

Development and validation of the immune risk (Imm-R) model. a Differentially expressed IRGs related with overall survival in univariate Cox regression analysis. P values are indicated by color scale on the side. Horizontal bars represent 95% confidence intervals. b Independent prognostic factors in multivariate COX regression analysis. P values are indicated by color scale on the side. Horizontal bars represent 95% confidence intervals. c Kaplan–Meier curves for patients with high- and low Imm-R score in the training set. d Kaplan–Meier curves for patients with high- and low Imm-R score in the validation set. e ROC curves for measuring the predictive value of the Imm-R model in the training set and validation set. f The nomogram of Imm-R model for predicting the three- and five-year survival probabilities. Points are assigned for four features. The score for each feature was calculated by drawing a line upward to the 'Points' line, and the sum of the four scores was 'Total Points'. The total points on the bottom scales correspond to the predicted three- and five-year survival. g The calibration plot of the nomogram predicting three-year survival. The x-axis is the nomogram-predicted survival and the y-axis is the actual survival. The reference line is 45° and indicates perfect calibration. h The calibration plot of the nomogram predicting five-year survival

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