Fig. 4

Enrichment map of the biological processes related to the top 500 genes identified by ANOVA included in the a congenital and b immobility disease classifier. Circles are referred to as “nodes” and the connectors are “edges”. Nodes represent specific biological pathways and node size represents the number of genes in the pathway. Edges connecting adjacent nodes represent overlapping pathways and edge width represents gene overlap size. The node colour represents enrichment score. Nodes that are blue are upregulated (enrichment score greater than zero) and nodes that are red are downregulated (enrichment score less than zero). The nodes are clustered into general functional groups