Skip to main content

Table 3 Chea3 transcription factor enrichment analysis of the LMWF5A-reduced cytokine signature

From: LMWF5A suppresses cytokine release by modulating select inflammatory transcription factor activity in stimulated PBMC

Rank Transcription factor Mean rank Overlapping genes
Sorted by mean rank
1 Basic leucine zipper transcription factor, ATF-like 3 (BATF3) 10.33 4
2 Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) (NFKB2) 17.25 5
3 Ets variant 3-like (ETV3L) 17.33 3
4 Interferon regulatory factor 8 (IRF8) 24 3
5 v-rel avian reticuloendotheliosis viral oncogene homolog (REL) 25 3
6 Zinc finger protein 267 (ZNF267) 32 3
7 Signal transducer and activator of transcription 1, 91 kDa (STAT1) 33.83 5
8 Musculin (MSC) 38 3
9 Basic leucine zipper transcription factor, ATF-like (BATF) 38.2 5
10 Early growth response 2 (EGR2) 40.33 3
Sorted by overlapping genes
93 v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA) 252.7 7
409 Jun proto-oncogene (JUN) 530 5
354 Estrogen receptor 1 (ESR1) 490.8 5
2 Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) (NFKB2) 17.75 5
7 Signal transducer and activator of transcription 1, 91 kDa (STAT1) 34.67 5
28 Zinc finger, BED-type containing 2 (ZBED2) 143.7 5
67 v-rel avian reticuloendotheliosis viral oncogene homolog B (RELB) 215 5
95 Ets variant 7 (ETV7) 257.3 5
242 SP140 nuclear body protein (SP140) 412 5
314 Basic leucine zipper transcription factor, ATF-like 2 (BATF2) 463.3 5