Fig. 5From: Tespa1 plays a role in the modulation of airway hyperreactivity through the IL-4/STAT6 pathwayTryptase expression in the mast cells of Tespa1−/− and WT mice after IL-4 stimulation. Primary pulmonary mast cells were derived from the lungs of mice, and IL-4 (20 ng/mL) was simultaneously applied for 1 and 4 h. Immunofluorescence was used to detect tryptase expression. a Immunofluorescence staining for p-STAT6. b Table of average tryptase fluorescence intensities. KO: Tespa1−/− mice; WT: wild-type mice. **P < 0.01 between groups. Mean ± SD, n = 10Back to article page