Table 2 Association between PDGFRα expression, clinicopathological parameters and RAS mutational status
Tissue samples | PDGFRα expression | P value | |
|---|---|---|---|
Low (n = 55) | High (n = 45) | ||
Age (years) | 0.447 | ||
< 50 | 13 (59.1%) | 9 (40.9%) | |
≥ 50 | 37 (54.4%) | 31 (45.6%) | |
Missing | 5 | 5 | |
Gender | 0.104 | ||
Male | 30 (49.2%) | 31 (50.8%) | |
Female | 25 (64.1%) | 14 (35.9%) | |
Missing | 0 | 0 | |
Location | 0.13 | ||
Colon | 43 (57.3%) | 32 (42.7%) | |
Rectum | 8 (40%) | 12 (60%) | |
Missing | 4 | 1 | |
Diameter of tumor (cm) | 0.048 | ||
≤ 5 | 23 (45.1%) | 28 (54.9%) | |
> 5 | 23 (65.7%) | 12 (34.3%) | |
Missing | 9 | 5 | |
Invasion of tumor | 0.644 | ||
T1 | 1 (100%) | 0 (0%) | |
T2 | 3 (50%) | 3 (50%) | |
T3 | 30 (56.6%) | 23 (43.4%) | |
T4 | 17 (47.2%) | 19 (52.8%) | |
Missing | 4 | 0 | |
Lymph node metastasis | 0.54 | ||
N0 | 20 (60.6%) | 13 (39.4%) | |
N1 | 18 (54.5%) | 15 (45.5%) | |
N2 | 14 (46.7%) | 16 (53.3%) | |
Missing | 3 | 1 | |
Histological gradation | 0.068 | ||
Well differentiated | 18 (72%) | 7 (28%) | |
Moderately differentiated | 33 (52.4%) | 30 (47.6%) | |
Poorly differentiated | 4 (33.3%) | 8 (66.7%) | |
Missing | 0 | 0 | |
RAS status | 0.000 | ||
Wild type | 17 (35.4%) | 31 (64.6%) | |
Mutated | 38 (73.1%) | 14 (26.9%) | |
Missing | 0 | 0 | |