Determinants of placental iodine concentrations in a mild-to-moderate iodine-deficient population: an ENVIRONAGE cohort study

Table 2 Concentration of the thyroid hormones FT₄, FT₃, and TSH in maternal blood and cord blood of 378 mother-neonate pairs and by tertiles of placental iodine concentration

Thyroid hormone	Total (n = 378)	Tertile 1 (n = 122)	Tertile 2 (n = 125)	Tertile 3 (n = 131)	p value for trend
Mother
FT₄, pmol/L	12.1 (2.0)	11.4 (1.9)	12.0 (2.0)	12.7 (1.8)	0.0001
FT₃, pmol/L	4.0 (1.0)	4.1 (0.9)	3.9 (1.0)	4.1 (1.2)	0.25
TSH, mIU/L	2.4 (1.3)	2.5 (1.2)	2.3 (1.4)	2.4 (1.3)	0.49
Neonate
FT₄, pmol/L	16.5 (2.0)	15.9 (2.2)	16.5 (1.9)	17.0 (1.9)	0.0001
FT₃, pmol/L	2.3 (0.6)	2.3 (0.5)	2.4 (0.6)	2.4 (0.6)	0.36
TSH, mIU/L	10.7 (7.6)	10.5 (7.0)	11.2 (8.6)	10.4 (7.3)	0.67
Placental iodine concentrations, µg/kg	26.2 (4.3)	21.6 (2.0)	25.8 (1.0)	30.9 (2.8)	–

Data are presented as mean (SD). Tertiles are based on the placental iodine concentration: I ≤ 24.2; 24.2 < I ≤ 27.5; and I > 27.5

ISSN: 1479-5876