Fig. 1
From: The dark side of the spoon - glucose, ketones and COVID-19: a possible role for ketogenic diet?
Ketone bodies and NLRP3/inflammasome activation. Protective effects of ketogenic diet and ßOHB on risk conditions associated with serious COVID-19 disease. ßOHB: Beta-hydroxybutyrate, AcAc: AcetoAcetate, MAVS: mitochondrial antiviral signalling protein, LPS: lipopolysaccharide, NLP3: NOD-, LRR- and pyrin domain-containing protein 3, ASC: Adaptor apoptosis associated Speck-like protein containing a Caspase Recruitment Domain (CARD), Pro-IL-1ß: pro-interleukin 1 beta, Pro-IL-18: pro-interleukin 18, DAMPs: damage-associated molecular patterns; PAMPs: pathogen-associated molecular patterns