Skip to main content

Table 1 Characteristics of the study population

From: Association between telomere length in peripheral blood leukocytes and risk of ischemic stroke in a Han Chinese population: a linear and non-linear Mendelian randomization analysis

Parameters Controls (n = 304) Cases (n = 431) P
Age, years 47 (35, 59) 57 (49, 63) 1.736 × 10–19*
Gender, n (%)    2.404 × 10–4*
 Male 130 (42.80) 244 (56.60)  
 Female 174 (57.20) 187 (43.40)  
Smoke, cigarettes/day, (%)    1.227 × 10–17*
 No 253 (83.20) 248 (57.50)  
 1–10 29 (9.50) 41 (9.50)  
 > 11 22 (7.20) 142 (32.90)  
Drink, (%)    8.893 × 10–5*
 No 221 (72.70) 252 (58.50)  
 Yes 83 (27.30) 179 (41.50)  
TL, kb 6.74 (5.18, 8.43) 6.44 (4.88, 8.93) 0.144
Height, cm 165.0 (159.0, 172.0) 167.0 (160.0, 172.0) 0.324
Weight, kg 66.95 (57.10, 77.58) 70.00 (63.00, 77.80) 0.003*
BMI, kg/m2 24.31 (22.08, 27.16) 25.27 (23.07, 27.39) 0.003*
SBP, mmHg 124 (113, 136) 138 (125, 150) 1.087 × 10–16*
DBP, mmHg 79 (72, 88) 82 (76, 91) 9.324 × 10–7*
FPG, mmol/L 5.00 (4.70, 5.50) 5.17 (4.61, 6.00) 0.053
TG, mmol/L 1.26 (0.86, 1.80) 1.34 (1.00, 1.87) 0.017*
TC, mmol/L 4.50 (3.99, 5.05) 4.22 (3.47, 4.99) 2.451 × 10–4*
HDL‐C, mmol/L 1.19 (1.01, 1.38) 1.08 (0.91, 1.24) 5.497 × 10–9*
LDL‐C, mmol/L 2.53 (2.12, 2.92) 2.46 (1.92, 3.00) 0.232
ApoA1, g/L 1.26 (1.14, 1.36) 1.19 (1.07, 1.29) 1.727 × 10–9*
ApoB, g/L 0.98 (0.85, 1.19) 0.93 (0.73, 1.11) 1.845 × 10–4*
ApoB/ApoA1 ratio 0.79 (0.66, 1.01) 0.77 (0.61, 0.96) 0.198
  1. TL telomere length, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, FPG fasting plasma glucose, TG triglycerides, TC total cholesterol, HDL‐C high‐density lipoprotein cholesterol, LDL‐C low‐density lipoprotein cholesterol, ApoA1 apolipoprotein A1, ApoB apolipoprotein B
  2. P < 0.05 is statistically significant