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Table 2 Demographical characteristics and periodontal conditions in dependence on rheumatoid arthritis (RA) and periodontitis (PD)

From: rs2476601 in PTPN22 gene in rheumatoid arthritis and periodontitis—a possible interface?

Variable

Control probands (without RA)

RA patients

p value**

No/level 1 PD n = 95

Level 2 PD* N = 161

All n = 111

No/ level 1 PD n = 85

Level 2 PD* n = 26

Demographical and anamnestic parameters

 Age, years (Median (25–75th IQR))

43.0 (38.0/51.0)

45.0 (38.0/52.0)

56.0 (48.0/63)

56.0 (47.0/63.0)

56.5 (50.0/64.5)

 < 0.001

 Male gender (%)

51.6

37.3

28.8

23.5

46.2

0.001

 Current smoking (%)

21.1

29.4

23.4

18.8

38.5

0.003

Periodontal conditions (Median (25–75th IQR)

 Plaque index (%)

39.0 (28.6/59.3)

57.0 (38.0/82.0)

35.7 (11.5/66.7)

27.0 (7.25/58.55)

64.1 (37.6/84.1)

0.176

 Bleeding on probing/tooth (%)

42.0 (23.1/63.0)

82.5 (56.0/100.0)

36.4 (18.2/69.6)

32.0 (16.7/63.25)

58.6 (32.4/89.8)

0.941

 Probing depth, mm

2.52 (2.27/2.76)

5.29 (4.52/6.4)

3.0 (2.7/3.7)

2.8 (2.6/3.2)

4.3 (3.78/4.96)

 < 0.001

 Clinical attachment loss, mm

2.8 (2.55/3.14)

6.1 (5.27/7.16)

3.4 (2.9/4.3)

3.1 (2.8/3.7)

5.15 (4.5/6.05)

 < 0.001

 Missing teeth (except 8th)

2.0 (0/4.0)

3.0 (1.0/6.0)

5.0 (2.0/10.0)

4.0 (1.0/10.0)

8.5 (5.0/15.25)

 < 0.001

  1. *Proximal attachment loss of ≥ 5 mm in ≥ 30% of teeth present
  2. **p value is given for statistical comparison of the control group without RA and no/level 1 PA (n = 95) with the RA total group (n = 111)
  3. Statistical comparisons were made by chi-square test including Yates correction for categorical variables. Continuous variables were analyzed by Mann–Whitney Test and presented as median (25th/75th-interquartiles; IQR, values not normally distributed)