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Table 2 Association of fibrinogen and Lp(a) categories with clinical outcomes

From: Prognostic utility of lipoprotein(a) combined with fibrinogen in patients with stable coronary artery disease: a prospective, large cohort study

Risk factor Tertile/range KM rates(%) Hazard ratio (95% CI) p value
Lp(a) categories Total (mg/dL)      < 0.001
  Lp(a)-L (< 10) 3.5 Reference  
  Lp(a)-M (10–29.9) 5.3 1.468 1.142–1.886 0.003
  Lp(a)-H (≥ 30) 5.6 1.580 1.227–2.033  < 0.001
Fibrinogen categories Total (g/L)      < 0.001
  Fib-L(< 2.84) 4.0 Reference  
  Fib-M(2.85–3.42) 4.4 1.123 0.867–1.455 0.380
  Fib-H(≥ 3.43) 6.1 1.631 1.282–2.074  < 0.001
Combined categories Total      < 0.001
  G1(Lp(a)-L + Fib-L) 3.3 Reference  
  G2(Lp(a)-L + Fib-M) 3.5 1.091 0.697–1.707 0.704
  G3(Lp(a)-L + Fib-H) 4.0 1.234 0.771–1.977 0.381
  G4(Lp(a)-M + Fib-L) 4.1 1.164 0.741–1.828 0.509
  G5(Lp(a)-M + Fib-M) 4.9 1.406 0.914–2.162 0.121
  G6(Lp(a)-M + Fib-H) 7.0 2.135 1.446–3.152  < 0.001
  G7(Lp(a)-H + Fib-L) 4.8 1.348 0.849–2.140 0.206
  G8(Lp(a)-H + Fib-M) 5.4 1.578 1.026–2.426 0.038
  G9(Lp(a)-H + Fib-H) 7.2 2.215 1.506–3.257  < 0.001
  1. Data are expressed as HR (95% CI). L low, M medium, H high