Fig. 5

Correlation of HLA-G, HLA-E and CREB staining with ccRCC patients’ overall survival. HLA-G (A, B), HLA-E (C), and CREB (D) staining intensity was correlated with OS survival in RCC demstrating that only CREB expression was significantly (p = 0.029) associated to patients’ OS. Note: No survival data were available for HLA-E negative cases and only few data on strong cases. Therefore, for this marker, the staining categories “negative/weak” and “medium/strong” were compared