The study of the association between immune monitoring and pneumonia in kidney transplant recipients through machine learning models

Table 5 The association of immune monitoring panel and prognosis of pneumonia in kidney transplant recipients

Parameters	Mild pneumonia (n = 29)	Severe pneumonia (n = 17)	P value
Monocyte HLA-DR, MFI ± SD	1068.59 ± 758.07	696.76 ± 410.57	0.127
Neutrophil CD64, MFI ± SD	584.17 ± 683.08	597.76 ± 462.88	0.657
CD3⁺ T cells/TBNK, mean ± SD (%)	75.42 ± 10.27	79.13 ± 13.85	0.065
CD3⁺ T cells, n ± SD (cells/μl)	657.84 ± 378.50	578.48 ± 348.62	0.453
CD8⁺ T cells/TBNK, mean ± SD (%)	34.31 ± 8.15	39.81 ± 11.96	0.070^*
CD8⁺ T cells, n ± SD (cells/μl)	301.85 ± 169.62	281.23 ± 184.66	0.702^*
CD4⁺ T cells/TBNK, mean ± SD (%)	40.42 ± 11.51	38.35 ± 15.46	0.635^#
CD4⁺ T cells, n ± SD (cells/μl)	363.68 ± 231.05	287.37 ± 201.42	0.255
NK cells/TBNK, mean ± SD (%)	14.17 ± 8.55	10.41 ± 9.01	0.056
NK cells, n ± SD (cells/μl)	135.60 ± 108.79	59.28 ± 39.50	0.027
B cells/TBNK, mean ± SD (%)	9.21 ± 6.62	9.75 ± 7.40	0.946
B cells, n ± SD (cells/μl)	73.46 ± 48.64	56.96 ± 38.63	0.255
TBNK, n ± SD (cells/μl)	874.48 ± 470.51	699.75 ± 382.39	0.219
CD4/CD8 ratio, mean ± SD	1.28 ± 0.59	1.10 ± 0.64	0.323^*
eGFR when discharge, ml/min/1.73 m²	78.27 ± 31.87	67.32 ± 35.23	0.285^*
Death with functioning graft, n (%)	0 (0)	3 (17.65)	0.045^§
Allograft loss, n (%)	0 (0)	1 (5.88)	0.370^§

HLA-DR human leukocyte antigen-DR, MFI median fluorescence intensity, SD standard deviation, NK cells natural killer cells, TBNK T, B and NK cells
^*Tested by Student's t-test. ^# Tested by Welch's t-test. ^§ Tested by Fisher’s exact test. Others tested by Mann–Whitney U test. Estimated glomerular filtration rate (eGFR) calculated by the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation

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