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Table 5 The association of immune monitoring panel and prognosis of pneumonia in kidney transplant recipients

From: The study of the association between immune monitoring and pneumonia in kidney transplant recipients through machine learning models

Parameters Mild pneumonia (n = 29) Severe pneumonia (n = 17) P value
Monocyte HLA-DR, MFI ± SD 1068.59 ± 758.07 696.76 ± 410.57 0.127
Neutrophil CD64, MFI ± SD 584.17 ± 683.08 597.76 ± 462.88 0.657
CD3+ T cells/TBNK, mean ± SD (%) 75.42 ± 10.27 79.13 ± 13.85 0.065
CD3+ T cells, n ± SD (cells/μl) 657.84 ± 378.50 578.48 ± 348.62 0.453
CD8+ T cells/TBNK, mean ± SD (%) 34.31 ± 8.15 39.81 ± 11.96 0.070*
CD8+ T cells, n ± SD (cells/μl) 301.85 ± 169.62 281.23 ± 184.66 0.702*
CD4+ T cells/TBNK, mean ± SD (%) 40.42 ± 11.51 38.35 ± 15.46 0.635#
CD4+ T cells, n ± SD (cells/μl) 363.68 ± 231.05 287.37 ± 201.42 0.255
NK cells/TBNK, mean ± SD (%) 14.17 ± 8.55 10.41 ± 9.01 0.056
NK cells, n ± SD (cells/μl) 135.60 ± 108.79 59.28 ± 39.50 0.027
B cells/TBNK, mean ± SD (%) 9.21 ± 6.62 9.75 ± 7.40 0.946
B cells, n ± SD (cells/μl) 73.46 ± 48.64 56.96 ± 38.63 0.255
TBNK, n ± SD (cells/μl) 874.48 ± 470.51 699.75 ± 382.39 0.219
CD4/CD8 ratio, mean ± SD 1.28 ± 0.59 1.10 ± 0.64 0.323*
eGFR when discharge, ml/min/1.73 m2 78.27 ± 31.87 67.32 ± 35.23 0.285*
Death with functioning graft, n (%) 0 (0) 3 (17.65) 0.045§
Allograft loss, n (%) 0 (0) 1 (5.88) 0.370§
  1. HLA-DR human leukocyte antigen-DR, MFI median fluorescence intensity, SD standard deviation, NK cells natural killer cells, TBNK T, B and NK cells
  2. *Tested by Student's t-test. # Tested by Welch's t-test. § Tested by Fisher’s exact test. Others tested by Mann–Whitney U test. Estimated glomerular filtration rate (eGFR) calculated by the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation