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Table 1 The clinical information of faecal microbiota transplantation donors

From: Gut microbiota from coronary artery disease patients contributes to vascular dysfunction in mice by regulating bile acid metabolism and immune activation

 

Con donor (n = 5)

CAD donor (n = 6)

P value

Gender (Male)c

3 (60%)

4 (66.67%)

0.819

Ageb

53.8 ± 8.1

66 ± 14.23

0.178

BMIb

22.3 ± 4.2

25.7 ± 5.1

0.247

Waistb

76.4 ± 10.4

93.5 ± 12.1

0.035

Gensini scorea

NA

32 (26.75, 46.25)

 

Current smokerc

2 (40%)

4 (66.67%)

0.377

Hypertensionc

1 (20%)

3 (50%)

0.122

Type 2 diabetesc

0

2 (33.33%)

0.154

TCb

4.6 ± 0.5

4.4 ± 1.6

0.74

TGb

1.1 ± 0.2

2.1 ± 0.8

0.338

LDL-Cb

2.8 ± 0.2

2.6 ± 0.4

0.662

HDL-Cb

1.27 ± 0.2

0.9 ± 0.1

0.092

FBGb

1.27 ± 0.2

10.23 ± 2.5

0.005

hs-CRPb

5.82 ± 0.6

38.5 ± 17.1

0.008

IL-1βb

2.66 ± 0.3

3.44 ± 0.9

0.030

TNF-αb

8.11 ± 5.4

20.4 ± 6.1

0.007

Drugs

 ACEI/ARBc

1 (20%)

3 (50%)

0.303

 Antidiabetic drugsc

0

2 (33.33%)

0.154

 Statinc

0

4 (66.7%)

0.022

  1. aMedian (IQR), bmean ± SD, cn (%)
  2. Continuous, normally distributed variables between two groups were analysed by Student’s t-test. Categorical variables were compared by the χ2 test. N/A not available, Gensini Score scoring system for determining the severity of coronary heart disease, BMI body mass index, TC total cholesterol, TG triglyceride, LDL-C low density lipoprotein cholesterol, HDL-C high density lipoprotein cholesterol, FBP fasting blood glucose, hs-CRP high sensitive C-reactive protein, IL-1β interleukin 1β, TNF-α tumor necrosis factor-α, ACEI/ARB angiotensin-converting enzyme inhibitors/angiotensin receptor blockers