Fig. 3

Comprehensive profiling of IRG-based clusters in sarcoma patients. a The consensus matrix heatmap defined four clusters from the 259 sarcoma patients. b Survival analysis showed that IRG-based clusters were significantly associated with OS. c Survival analysis showing that IRG-based clusters were not significantly associated with PFS. d Tumor microenvironment scores of the four clusters. e The expression levels of five immune checkpoints (PD-1, PD-L1, BTLA4, CTLA4, and LAG3) in the four clusters. f Histogram of the infiltration levels of 12 significant immune cells in the four clusters. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001. IRG Immune-related gene, OS Overall survival, PFS Progression-free survival