Fig. 7
From: MiR-199a-3p/5p participated in TGF-β and EGF induced EMT by targeting DUSP5/MAP3K11 in pterygium
The effects of TGF-β and EGF on expressions of DUSP5 and MAP3K11 could be regulated by miR-199a-3p and miR-199a-5p. a–d HCEs were induced with TGF-β (10 nM) and EGF (20 nM) for 7 days. The expressions of miR-199a-3p, miR-199a-5p, DUSP5 and MAP3K11 were detected by qRT-PCR analysis (*p < 0.05, **p < 0.01). e The protein expression of DUSP5 and MAP3K11 were analyzed with western blot (*p < 0.05, **p < 0.01). f, g. The mRNA changes of DUSP5 and MAP3K11 before and after induction and transfection (*p < 0.05, **p < 0.01, ***p < 0.001). h, i The protein changes of DUSP5 and MAP3K11 before and after induction and transfection (*p < 0.05, **p < 0.01)