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Table 10 Composition of human platelet lysate reported in literature: growth factors and proteins

From: Human platelet lysate to substitute fetal bovine serum in hMSC expansion for translational applications: a systematic review

First author Year Estimated? Type of Medium PDGF (ng/ml) PDGF-AA (ng/ml) PDGF-AB (ng/ml) PDGF-BB (ng/mL) TGF-Beta (ng/ml) VEGF (ng/ml) bFGF (ng/ml) EGF (ng/ml) BDNF (ng/ml) IGF-1 (ng/ml) HGF (ng/ml) Beta-NFG Protein Tot (mg/ml) Albumin (mg/ml)
Barro 2019 Y hPL    80.00   32.00 0.17 0.40 3.80 100.00 80.00 0.13   58.32 41.00
Barro 2019 Y I-hPL    125.00   33.00 0.40 0.42 5.90 80.00 80.00 0.25   26.85 17.00
Barro 2019 N DVI-hPL    8.16   35.17 0.31 0.35 4.70 25.73 35.17 0.24   26.27 16.00
Chen 2018 N SDPL    45.00 11 75.00 0.40 0.55 0.85 20.00 17.50 0.12   56.00  
Chen 2018 N FTPL    45.00 11 75.00 0.40 0.55 0.85 20.00 17.50 0.12   56.00  
Chen 2018 N GBPL    45.00 11 75.00 0.40 0.55 0.85 20.00 17.50 0.12   56.00  
Chen 2018 N GBHPL    45.00 11 75.00 0.40 0.55 0.85 20.00 17.50 0.12   56.00  
Mangum 2017 N hPL   4.57 17.84 5.24 5.5 0.75 5.5 0.5 5.5   0.5    
Bernardi M 2017 N hPL   0.00 0.03 0.01 0.05 0.00 0.00 0.00   0.00     
Bernardi M 2017 N PR-SRGF   0.01 0.14 0.01 0.04 0.00 0.00 0.00   0.11     
Pierce 2017 N hPL     10.70   0.80 0.20 3.40      54.00  
Viau 2017 N PR-hPL    28.78   55.20 0.65 0.15 1.48   32.55     
Viau 2017 N hPL    28.78   55.20 0.65 0.15 1.48   32.55     
Escobar 2016 N hPL     0.42 0.15 0.00 0.30 0.42   0.00     
Shirzad 2016 N UCB-PL    577.97   56.04   0.06    501.62    90.46  
Shirzad 2016 N PB-PL    391.62   29.31   0.06    325.50    49.14  
Suri 2016 Y hPL 70.00     250.00 0.90   0.20       
Suri 2016 Y PhPL 40.00     210.00 1.20   0.27       
Witzeneder 2013 N hPL p     18.11 32.74   0.36 0.01   33.14    61.20  
Witzeneder 2013 N hPL n     22.14 54.86   0.17 0.01   4.42    7.70  
Witzeneder 2013 N huS     2.38 4.89   0.00 0.01   85.98    66.60  
Mojica-Henshaw 2013 N hPLFreeze/thaw -196/4 °C   21.00 50.00 13.90    0.19 4.40      58.64  
Mojica-Henshaw 2013 N hPL Freeze/thaw -80/4 °C   13.70 43.80 8.70    0.16 3.60       16.12
Shanskii 2013 N hPL   6.91 3.98 8.20 16.30 0.15     108.70    26.00 42.50
Fekete 2011 N PL-PCC   239.41 571.73   139.03 0.33 0.50        
Crespo-Diaz 2011 N hPL 10.00     125.00 0.45 0.20 20.00   130.00     
Shichinoche 2011 N hPL     0.14 2.85     0.79   0.00 0.00   
Xia 2011 N hPL    0.00   5.15   0.04    0.00     
Schallmoser 2007 N hPL   7.42 40.46    0.00 0.06 0.19       
Doucet 2005 N hPL    30.89   50.84   0.09    106.67     
Doucet 2005 N PPP    0.24   0.51   0.00    107.41     
Mean Values     40.00 36.63 99.06 7.50 57.24 0.40 0.23 2.77 35.82 78.81 0.13 0.00 49.95 26.52
Shanskii 2013 N FBS   0.14 0.03 0.00 0.85 0.00     64.10    58.64 34.45
Shichinoche 2011 N FBS     0.14 1.27     0.00   0.00 0.00   
Doucet 2005 N FCS    0.00   6.21   0.00    72.82     
Mean Values      0.14 0.01 0.07 2.78 0.00 0.00   0.00 68.46 0.00 0.00 58.64 34.45
Shichinoche 2011 N FBS-BMSCs cultures     0.00 1.73     0.03   1.72 0.00   
Shichinoche 2011 N hPL-BMSCs cultures     0.00 3.84     0.05   2.55 0.00