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Table 1 Immunohistological scoring of lung metastases in HTM and TM

From: A novel rabbit derived anti-HER2 antibody with pronounced therapeutic effectiveness on HER2-positive breast cancer cells in vitro and in humanized tumor mice (HTM)

Score

Description

0

No tumor cells

1

1–5 tumor cells

2

Single cells distributed throughout organ

3

Cell cluster/metastases formation

  1. SK-BR-3 transplanted HTM and TM were immunohistologically stained using anti-HER2 antibodies and tumor cells scored as indicated (count of tumor cells/high power field)