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Table 2 Association of mRNA expression levels of GYPC, NME1 and SLIT2 with the pathological features

From: Identification and validation of smoking-related genes in lung adenocarcinoma using an in vitro carcinogenesis model and bioinformatics analysis

Factor Case GYPC NME1 SLIT2
Gender
 Male 238 8.31 ± 0.91 10.95 ± 0.86 7.44 ± 1.57
 Female 277 8.52 ± 0.94* 10.80 ± 0.84* 7.63 ± 1.47
Age
 < 60 136 8.37 ± 0.99 11.00 ± 0.78 7.32 ± 1.61
 \(\ge \)60 360 8.45 ± 0.91 10.82 ± 0.88* 7.63 ± 1.48*
Invasion depth
 T1 169 8.63 ± 0.77 10.67 ± 0.88 7.89 ± 1.31
 T2 277 8.32 ± 0.99** 10.96 ± 0.76** 7.35 ± 1.57**
 T3 47 8.38 ± 0.92 10.97 ± 1.11 7.35 ± 1.69*
 T4 19 7.99 ± 0.87** 11.07 ± 0.98 7.34 ± 1.29
Lymph node metastasis
 N0 331 8.43 ± 0.95 10.78 ± 0.85 7.58 ± 1.55
 N1 96 8.43 ± 0.89 11.04  ±  0.85** 7.34 ± 1.46
 N2 74 8.27 ± 0.85 11.10 ± 0.81** 7.47 ± 1.44
 N3 2 8.46 ± 0.19 11.04 ± 1.07 6.76 ± 0.46
Distant metastasis
 M0 346 8.43 ± 0.92 10.95 ± 0.85 7.50 ± 1.48
 M1 25 8.06 ± 0.88 10.96 ± 0.91 7.66 ± 1.70
TNM stage
 I 275 8.46 ± 0.92 7.60 ± 1.49 10.78 ± 0.82
 II 122 8.47 ± 0.99 7.47 ± 1.59 10.87 ± 0.85
 III 84 8.30 ± 0.83 7.36 ± 1.41** 11.12 ± 0.89
 IV 26 8.17 ± 1.02 7.78 ± 1.78 10.92 ± 0.91
  1. Note: The data was presented as in log\(_{2}\)(x+1) transformed RSEM normalized count. LUAD, lung adenocarcinoma; TCGA: The Cancer Gene Atlas; TNM: tumor-node-metastasis; stage RSEM: RNA seq by expectation-maximization. * p<0.05, versus the first group of the corresponding feature. ** p<0.01, versus the first group of the corresponding feature